Sentence examples for binding affinity and specificity from inspiring English sources

These key residues are all known to be critical in PRM's binding affinity and specificity to the WW domain27.

In conjunction with the numerous hydrophobic contacts, several polar interactions are also observed at the protein SL1067 interface, and these may contribute to binding affinity and specificity.

Linear (linG7A5) and cyclic (cyG7A5) grafted peptides were synthesized to test their binding affinity and specificity.

Its binding affinity and specificity to CD40L were confirmed by Surface Plasmon Resonance (SPR) measurements.

The LNA containing probes display high binding affinity and specificity to DNA containing mutations, which allows for the detection of mutation abundance with an intercalating EvaGreen dye.

The J591 ScFv showed binding affinity and specificity to cell extracts containing PSMA and PSMA-expressing prostate cancer cells.

Triad Therapeutics' proprietary technologies enable dramatic increases in both the speed of lead compound generation and the quality (binding affinity and specificity) of the compounds produced.

Tetrahydroisoquinoline derivatives are a class of selective estrogen receptor modulators (SERMs) with high binding affinity and specificity exhibiting up to 50 folds for ERα over ERβ.

Mini-yCD3 displayed similar antigen-binding affinity and specificity to yCD3.

Several studies have shown that the tethering of multiple binding modules can enhance RNA-binding affinity and specificity, a strategy also commonly used in DNA recognition.

Through the description of the key mass and one-off movements observed in metal-dependent HDACs, here we highlight the impact of flexibility on drug-binding affinity and specificity.