Sentence examples for binding affinity and binding from inspiring English sources
The introduction of this technology into both research and clinical settings necessitates the development of rapid and accurate means of evaluating both the binding affinity and binding specificity of designed zinc finger domains.
To clarify the possible mechanism by which novel 8-hydroxyquinoline-5-sufonyl 1,4-diazepine derivatives act as anti-schistosomal agents, molecular docking of all new compounds was carried out using Molsoft ICM pro 3.5-0a to investigate the binding affinity and binding mode to thioredoxin glutathione reductase enzyme (TGR), a potential drug target for anti-schistosomal agents.
By incorporating these findings into an improved design of the peptides that make up the synbody, it should be possible to improve the binding affinity and binding specificity.
This leads to the question how proteins generate binding affinity and binding specificity [ 50].
This will be particularly useful for studying binding of agents to receptors, allowing values to be derived for receptor number, binding affinity and binding potential.
Kr2 and nr2 denote the binding affinity and binding cooperativity between the repressor x r 1 * and the corresponding promoter-RBS component in the second stage, respectively.
In this study, we show that the p52 Bcl3 complex binds to both A/T- and G/C-centric κB sites; however, the binding affinities and binding modes are different, leading to different transcriptional outcomes.
While some distinct HLA-alleles can present the identical peptide, the polymorphism may cause disparate HLA molecules to have different peptide binding affinities and binding kinetics, which will also affect TCR recognition (Kloverpris et al., 2013).
Because it is the MG-H1 moiety specifically that binds to the V domain, MG-H1-containing peptides or proteins, which have different secondary and tertiary structures, exhibit similar binding affinities and binding surfaces.
