Sentence examples for binding affinities within a from inspiring English sources

The majority of the peptides present in both dataset have very similar binding affinities, and 97.5% of those peptides share annotated binding affinities within a 1.5 fold range.

Each MHC allele has a unique range and distribution of predicted binding affinities within a protein.

This observation renders the redistribution of PG part of a final common pathway in ARVC pathogenesis, not merely stemming from disruptions in binding affinities within the desmosomal plaque.

The mutation causes increased binding affinities within the SNARE complex and disrupted exocytotic vesicle recycling in vivo, limiting neurotransmission under continued stimulation (76).

The Bdr Snap-25 missense mutation results in increased binding affinities within the soluble NSF attachment protein receptor (SNARE) complex, leading to impaired exocytotic vesicle recycling and exocytosis and a reduction in the amplitude of excitatory postsynaptic potentials [ 3].

For 87 out of 644 ligands, the criterion (±5%) did not result in any selected peptides because these ligands were predicted by NetMHCIIpan to be very strong binders, and no other peptides were found within the source protein with a binding affinity within the range of -5% of the reference ligand binding affinity.

A single amino acid substitution (I67T) results in an increased binding affinity within the core SNARE complex, preventing the normal recycling of synaptic vesicles (36).

2, 3 Darunavir (DRV) represents a specifically engineered inhibitor of HIV-protease, designed to have a greater binding affinity within the active site of the viral enzyme.

Potential PWMs which corresponded to the binding sequence of a specific transcription factor were selected based on the binding affinity within DHS sites in the gene promoter region, as detailed in the methods.

In particular, 2-deoxo-2-phenylflavin-5-oxides exhibited the highest potential binding affinity within the binding pocket of PTK.

The HIV-1 epitopes were subsequently ranked by their predicted HLA-binding affinity within all HIV proteins.