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Although Ehrlich himself described the observation of the lack of staining, his thoughts were not as insightful as Ridley's in 1695 since he presumed, as mentioned above, that the difference was due to the different binding affinities of different tissues to different dyes.
To investigate enzyme ligand interactions in yeast hexokinase isoform PII under physiological conditions, we utilized the technique of Saturation Transfer Difference NMR (STD NMR) to monitor binding modes and binding affinities of different ligands at atomic resolution.
Here we evaluate the performance of a molecular dynamics based method for predicting the binding affinities of different types of human thrombin inhibitors.
Discrepancies are found between the results of the binding affinities of different new TSPO radiotracers, and they showed heterogeneity in binding potentials in humans [9, 16, 41, 42].
In this study we look into whether the binding affinities of different cellulase variants vary between dislocations and the surrounding cell wall.
The identical spatial arrangement of 4 trimeric HA units in the pre-complex relative to the glycans on the array platform, homogenizes the avidity effects across different HAs and hence permits quantitative comparison between glycan binding affinities of different HAs.
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We present a computational investigation of binding affinity of different types of drugs with chitin nanocarriers.
Recent work has focused on the binding affinity of different strains of influenza virus for specific cell receptors within the respiratory tract [18] [21] and it is believed that this difference in affinity between human and avian strains may in part be responsible for the difference in severity between the two strains, though the reasons for this are currently not well understood.
Here, however, by measuring the binding affinity of different export-competent NES for Crm1, we find no evidence of a correlation between Crm1 affinity and the ability to potentiate CSR.
The oxygen binding affinity of different combinations was epistatic, such that the HHH, LLL and LHH combinations showed the highest affinity while for all other combinations lower values were reported.
Techniques from the signal-processing field were used, in particular the Hann digital filter, to calculate the relative binding affinity of different regions based on previously published in vitro binding data.
More suggestions(18)
binding affinities of various
binding affinities of disparate
binding affinities of wild-type
binding affinities of orthologous
binding strengths of different
binding affinities of particular
binding preferences of different
binding efficiencies of different
binding scores of different
binding specificities of different
binding locations of different
binding affinities of methylated
binding domains of different
binding properties of different
binding affinities of regulatory
binding affinities of multiple
binding affinities of representative
binding affinities of nicotinic
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