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This trend tracks the thermodynamic binding affinities for these sugars and demonstrates that the 'on' rate is the key factor determining the binding constant.
The binding affinities for these three F1SBPs indicated that they might be involved in the import of intact mucin oligosaccharides as well of GNB.
These results suggest that the GR binding affinities for these three drugs are roughly equivalent.
To support this conclusion, the authors should either provide binding affinities for these interactions or perform reciprocal pulldowns with the hypothesized interaction partners.
However, unexpectedly, this was also true for the majority of the QacR mutants with Be and Dq; i.e., nearly all displayed binding affinities for these drugs within 2-fold of that of wt QacR (Table 2).
It was also proposed, that the varying effects of CIM on P450 enzymes could be attributed to different CIM binding affinities for these mixed function oxidases (Faux and Combes, 1993).
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Experimental binding affinities for the protein-ligand complexes were taken from the PDBBind Database [69].
The DNA binding affinities for the target dicationic bis-guanidines were assessed by ΔTm values.
Furthermore, DCs appear to have disparate binding affinities for the different mannosylated OVA antigens.
Further, the binding affinities for the selected secondary antigens are often quite weak.
First, we calculate binding affinities for the probes and target DNA in the hybridization solution.
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