Sentence examples for binding affinities for specific from inspiring English sources

Many of these programs base predictions upon existing quantitative peptide binding affinities for specific MHC molecules [26], [27], [28], [29].

Slow nucleotide substitution rates, in particular allelic lineages (HLA-DRB1*04, *15, and *16), may be necessary to retain the binding affinity for specific peptides.

To evaluate the relative importance of these specific interactions, the salt dependence of the binding affinity for the specific substrate (DS) was measured by monitoring the increase in 2-AP fluorescence as a function of hUNG concentration using various concentrations of potassium fluoride.

This adaptation requires the development of methods for (i) generating candidate structures and (ii) evaluating and prioritizing these structures with respect to their binding affinity for a specific guest.

These features enhance our ability to calculate and estimate the sequences that yield the highest binding affinity for a specific RBP.

GAL4 possesses high binding affinity for a specific 17-bp oligonucleotide sequence (5'-cggrnnrcynyncnccg-3', GAL4rec) and acts as a nuclear localization signal (NLS) [ 18].

We referred to SNPs that result in a significantly higher or lower PWM scores compared to the major alleles as having an increase or decrease of binding affinity for the specific TF, respectively.

The first step to achieve this goal is to understand the molecular basis of high binding affinities of specific pro-apoptotic BH3 peptides for Mcl-1 and A1.

The results suggest that OsSMF1 has specific binding affinities for the three motifs and that it functions in a wide variety of seed developmental processes.

The results of this study suggest that OsSMF1 is one of the key transcription factors that functions in a wide range of seed developmental processes with different specific binding affinities for the three DNA-binding motifs.

The endothelin effects are mediated through two G-coupled protein receptors in mammals, endothelin receptor A (EDNRA) and endothelin receptor B (EDNRB), with distinct and specific binding affinities for native and synthetic ligands (Sakurai et al., 1992).