Sentence examples for binding affinities for human from inspiring English sources
These compounds (1a and 2a) also possessed weak binding affinities for human CCR1 receptors.
Out of 2185 transmembrane proteins, four epitopes with high binding affinities for human and mouse MHCII molecules were selected through computational screening.
The effects of increasing alkyl chain length of ω-amino acid on the functional activities and the receptor binding affinities for human melanocortin receptors (hMC-Rs) were studied.
In addition, although protein A and protein G have strong binding affinity for human IgGs, protein G has moderate affinity and protein A has weak affinity for mouse IgGs commonly used in research.
In IAH, the presence of 12 heavy atoms and a high potential energy of 50.33 kcal/mol suggested that this ligand molecule has a good binding affinity for human ApoE4.
The combination of high-binding affinities for human melatonergic receptors (h-MT1R and h-MT2R) and fluorescent properties, derived from the inclusion of melatonin pharmacophoric elements in the coumarin scaffold, yielded suitable candidates for the development of MT1R and MT2R fluorescent probes for imaging in biological media.
However, in previous studies, a single mutation D190N of A(H1N1) HA was shown to result in a lower binding affinity for human-like α(2,6) receptors, and a higher binding affinity for avian-like α(2,3) receptors [64].
This study demonstrates that the modification of hyaluronan (hyaluronic acid; Hya) and chondroitin sulfate (CS) with sulfate groups leads to different binding affinities for recombinant human transforming growth factor-β1 (TGF-β1) for comparable average degrees of sulfation (DS).
Most notably, novel granisetron conjugates 14, 16, 18, 27 and 28 have similar binding affinities for the human 5-HT3AR as measured for the parent compound 1.
