Sentence examples for binding affinities for different from inspiring English sources

Finally, we investigate the ability of our approach to capture variations in binding affinities for different peptide sequences.

However, it is not yet clear whether this change results from increased stability of DNA-bound complexes or alterations in binding site preferences, as none of these studies have directly investigated whether the interactions with Notch and Mastermind-like proteins might alter the DNA binding site preferences of CSL and/or its binding affinities for different DNA sequences.

Six of the 29 SNPs locate within intronic regulatory elements, two of which are predicted to have allele-specific binding affinities for different transcription factors [ 75].

Synthetic SRIF analogues such as SMS-201-995 (Sandoctreotidectreotide), RC-160 (Vapreoctastatinandatin) and BIM-23014 (Lanreotide, somatuline) have been developed which have varying binding affinities for different receptor subtypes.

The protein mutagenesis experiments therefore give a more nuanced view of how EF-Tu achieves its broad range of binding affinities for different tRNA bodies than was previously obtained from tRNA mutagenesis experiments.

The results here indicate that identical fragments could have modestly different intrinsic binding affinities for different CYP isoforms simply because the resting states of these enzymes vary in the strength of the starting Fe3+ H2O bond.

Our findings provide a foundation for the systematic design of biomolecules with selective binding affinity for different chitin polymorphs.

Many species express several distinct Importin-α proteins with variations in binding affinity for different NLS sequences [ 68].

Many enzymes have broad ranges of binding affinity for different substrates that allows them to affect a variety of cellular pathways.

This is difficult to do with microarrays, because sequence-specific effects result in huge variations in binding affinity for different microarray probes and the signal associated with each probe cannot be considered a measure of relative abundance of different genes within a sample.

It was suggested that the catalytic pocket may adopt different conformations depending on the nature of the substrate, and the small-molecule inhibitors may show different binding affinities for these different conformations (or not bind at all).