Sentence examples for binding affinities for both from inspiring English sources

The enzyme shows reduced binding affinities for both substrates and inhibitors.

However, one group has used ITC to show that the isolated tandem RBDs of RGS14 have micromolar binding affinities for both recombinant H-Ras and Rap1B [16].

Additionally, the Zn II) binding affinities for both complexes fall into the same range.

The IC50 ratios of Complex 2 indicated that the protein(s) forming this complex exhibited similar binding affinities for both the DBA/2J and 129B6 DNAs.

MD simulations were performed to approximate binding affinities for both d- and l-nucleosides, as well as nucleoside analogues bound to selected dCK variants.

A suitable dataset for validation would be one that reports binding affinities for both wild-type and mutant proteins with same ligand, performed in a uniform experimental environment, for large number of proteins.

Asym-mAb23 has enhanced binding affinity for both FcγRIIIa and FcγRIIa at the highest level of previously reported Fc variants.

In particular, ortho substitution with the nitro group results in mediocre binding affinity for both receptor subtypes (σ1: 7d vs 8d vs 9d; σ2: 7d, 8d and 9d), 2″-N).

Twelve HepG-2 and seventeen HeLa cell high-activity binding peptides (HABPs) have been identified in SIAP-1, 8 of them having high specific binding affinity for both cell lines.

Their interaction with the EGFR or PDGFR reduces the binding affinity for both ATP and substrate, causing a reduction in the catalytic activity of the enzyme, thus making them an allosteric inhibitor.

Hazlett et al. [30] and Desrosiers et al. [31] revealed that TpTroA has high binding affinity for both Zn2+ and Mn2+, but Zn2+ is considered to be the primary substrate of TpTroA [32].