Sentence examples for binding affinities and specificities from inspiring English sources
Hence, the different degrees of p21 and p27 disorder specifically tune their binding affinities and specificities toward Cdk-cyclins in vitro and in vivo.
Molecularly imprinted polymers (MIPs) are tailor-made synthetic materials with binding affinities and specificities comparable to those of antibodies and enzymes.
In conjunction with in silico analysis, this set of structures informs us about the design of putative ligands with enhanced binding affinities and specificities to different Siglecs, and provides data with which to test the effectiveness of different computational drug design protocols.
Interestingly, the relative binding affinities and specificities of the TA sequences were found to correlate with the energy of the structures predicted by MFOLD [34] (Table S1).
Similar binding affinities and specificities were observed over a wide range of salt concentrations (150 to 900 mM) and pH conditions (pH 5.0 to 9.5).
Results: Our study revealed that the chemically diverse compounds bound to ERs via varied sets of protein ligand interactions, reflecting their differential activities, binding affinities, and specificities.
There are typically two binding assays to "de-orphanize" OBPs, i.e., to measure their binding affinities and specificity towards physiologically and behaviorally relevant odorants (ligands).
The method accounts for the context-dependent DNA-binding activities of zinc fingers, a parameter that previous studies have suggested is important for creating arrays with high DNA-binding affinities and specificities [30], [37] [42].
