Sentence examples for binding affinities and kinetics from inspiring English sources
The first tool (MITOMI) consists of a microfluidic platform that enables quantitative measurement of binding affinities and kinetics for up to 4,000 interactions in parallel.
The binding affinities and kinetics were further analysed by Surface Plasmon Resonance (SPR) experiments (Table 2).
Nanodisc technology is as a powerful tool for measuring quantitative binding affinities and kinetics for membrane proteins interacting with their ligands.
The crystal structures and an analysis of the binding affinities and kinetics of CTLA-4 with its ligands suggest that CD86 monomers bind to CTLA-4 dimers, whereas CD80 dimers bind two adjacent bivalent CTLA-4 dimers, building a lattice-like network (Fig. 1) [ 6- 8].
Binding affinities and kinetics of the antibiotics to these model membranes were influenced by electrostatic interactions with the different lipid backgrounds, in addition to ligand affinities.
Bacterial microarrays enable profiling of accessible carbohydrate structures and screening of their recognition by host receptors, also providing information on binding avidity, while the QCM approach allows determination of binding affinity and kinetics.
Based on the mutagenesis mapping of bH1 and bH1-44, we generated Ile29A+Tyr32A (LC) or Arg50A+Arg58A (HC) mutations in bH1-44, whicompletelyely disrupted the binding to VEGF or HER2, respectively while maintaining the binding affinity and kinetics for the other antigen (Figure 2).
The binding affinity and kinetics of Nimotuzumab has been shown to be similar between wtEGFR and EGFRvIII [ 41].
To better understand the difficulties we had in observing Tie2 activation by VT, we sought to characterize the binding affinity and kinetics of VT to Tie2.
For instance, different viruses possess different physical and chemical properties, including shape, rigidity, net charge, charge distribution, hydrophobicity, binding affinity and kinetics to the Protein A ligand and the antibody.
In sensitive cellular and biochemical studies of two murine IL4 allotypes, we found that site 1 epitope variation is functionally neutral with respect to IL4Rα binding affinity and kinetics as well as signalling IL4-dependent cellular responses.
