Sentence examples for binding affects from inspiring English sources

To investigate in more detail how FOXL2 works, Georges et al. grew mouse granulosa cells in the laboratory to identify the DNA sequences where FOXL2 will bind, and to uncover how this binding affects gene expression.

Ligand binding affects the network as well.

We show that ligand binding affects the enzyme's conformational dynamics, shaping the free-energy landscape toward the next stage of the catalytic cycle.

It is important to understand how external free energy, including electrochemical potential of the substrate, drives the thermodynamic process of the transporter, and how the substrate binding affects the kinetic property of the transporter.

It is evident that binding affects M y for both self-ligated and elastically ligated brackets in a similar way: onset occurs at the binding angle and the rate of increase is similar for both types.

Whereas in academia a typical investigation might entail determining "the affinity of an antibody to its receptor and the effects on signaling," the commercial question, he clarifies, would focus more on "how antibody binding affects other targets for toxicity and on the overall cellular clinical response to the antibody, rather than on the details of the signaling pathways".

We therefore determined whether exosomes from ARPE-19 cells bind C3 and/or CFH and if CFH binding affected the amount of C3 associated with the exosomes.

Although four of the five histidine residues are located far from the active site, ligand binding affected their pKa, t1/2 or both.

How does ligand binding affect protein stability?

We then evaluated whether AChE binding affected some generic physical properties of PrP amyloid fibrils.

Based on the reported crystal structure of FARS2 [30], we predict that this mutation will disrupt ATP binding, affecting aminoacylation efficiency.