Sentence examples for binding activity which is from inspiring English sources

Transient nicotine stimulation activates Stat3/ERK1/2 and leads to the induction of Stat3 and NF-κB DNA binding activity, which is associated with cyclin D1 expression and cell proliferation in bladder cancer cells.

Impaired IKZF2 binding could also facilitate the access of SP1 (Th1 response) through its binding activity, which is present in the vicinity of SPP1c.-1301G>A.

In contrast to C. arabica, C. canephora has more proteins annotated as containing binding activity, which is extended for the binding activity branch child terms of nucleic acid binding, DNA and RNA binding activities, transcription regulation and transcription factor activities.

DCA induces clear AP-1 DNA binding activity, which is reduced by addition of antibodies against Fra-1 and c-Jun but not by the anti-c-Fos antibody.

A primary antibody against Nrf2 followed by a horseradish peroxidase (HRP -conjugated secondary antibody allowed a colorimetric readout of Nrf2 binding activity, wHRP -conjugateded asecondarym ± SD.

Incubation of human lung adenocarcinoma A549 cells with 25 μM Gefitinib resulted in phosphorylation and activation of p53 such as enhanced DNA binding activity, which was accompanied by the upregulation of PUMA (p53 upregulated modulator of apoptosis) and Fas, and downregulation of survivin and XIAP (X-linked inhibitor of apoptosis protein).

Thirdly, a divalent form of the DT389-scFv construct, containing tandem scFv domains, had a 10-fold higher binding activity, which was exactly reflected in a 10-fold increase in potency.

t-Darpp overexpression led to increased CREB binding activity, which was also reversible by Darpp-32.

Overexpression of t-Darpp also led to increased CREB binding activity, which was also reversible by Darpp-32.

In parallel, the digested protein was also assayed for target binding activity, which was compared to that of the parental protein.

Although the D. buzzatti THAP domain was purified in the presence of a chelating agent, it retained DNA binding activity, which was not enhanced by the addition of zinc chloride (Fig. 3B).