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Exact(18)
Constitutive activation of AP-1 leading to its high binding activity was observed in most of the esophageal tumors, irrespective of their clinical stage and histo - pathological grade; whereas normal adjacent tissues showed low or no AP-1 activation.
Notably, little to none DNA binding activity was observed with nuclear extracts of tumor tissue.
Note, no HNF6 DNA binding activity was observed with control Caco-2 cell cultures (see Fig. 1C).
The best binding activity was observed when the ratio of RelB/RelE reached 2∶1 (Fig. 2B, lane 6).
No binding activity was observed for the other two RelB-like antitoxin proteins (RelB and RelF), even at very high protein concentrations (Fig. 2, 3).
A similar loss of DNA binding activity was observed upon addition of the iron chelator bipyridyl to holo NsrR (data not shown).
Similar(42)
As shown in Fig. 3B, no differences in Ku DNA ends binding activity were observed during adipocyte differentiation.
Hence, E-box binding activity is observed in the Y1H and in fluorescence studies under more diverse buffer conditions for the more stably folded ArntbHLH-C/EBP than for ArntbHLH.
As shown in Figure 3A, high constitutive activation of NF- κB DNA-binding activity was observed in nuclear extracts prepared from nonpigmented SKMEL-188 melanoma cells, as compared with extracts prepared from pigmented cells.
As expected, a rapid and strong NF-κB DNA-binding activity was observed in response to a 30 min treatment with TNFα (Figure 5A, lane 2) and VPA alone caused no induction of NF-κB binding activity even after a 90 min treatment (Figure 5A, lanes 4 and 7).
DNA-binding activity was observed from 4 h treatment onwards with 100 nM rapalog (Fig. 2D) and further increased with time.
More suggestions(18)
binding site was observed
binding activity was indicated
binding activity was increased
binding preference was observed
binding activity was verified
binding event was observed
binding activity was affected
binding displacement was observed
binding activity was expected
binding activity was confirmed
binding activity was accompanied
binding mode was observed
binding capacity was observed
binding activity was determined
binding affinity was observed
binding activity was induced
binding activity was assessed
binding activity was blocked
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