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To test whether the decreased HA-receptor binding activity was accompanied by a decrease in viral infectivity in chicken eggs when the residues 222 and 225 were changed in the Panama clade, we compared the replication efficiency in chicken eggs of the viruses bearing different amino acids at residues 222 and 225 within the same antigenic Panama clade (see Methods S1).
Similar(59)
The fact that the cases with DNA-binding activity were accompanied with MDM2 protein isoforms' overexpression is indicative of a 'gain of function' phenotype.
The CTL activity was accompanied by high levels of IFN-γ production after Ad5F35-CTL·Th stimulation.
In CHD animals, the increased islet TH activity was accompanied by a decreased NE content [ 24].
Interestingly, the enhancement in antiproliferative activity is accompanied by the disappearance of skin phototoxicity.
This inhibitory activity is accompanied by an increase in the number of apoptotic cells.
A list of these activities was accompanied by clarifying examples.
Incubation of human lung adenocarcinoma A549 cells with 25 μM Gefitinib resulted in phosphorylation and activation of p53 such as enhanced DNA binding activity, which was accompanied by the upregulation of PUMA (p53 upregulated modulator of apoptosis) and Fas, and downregulation of survivin and XIAP (X-linked inhibitor of apoptosis protein).
These activities were accompanied by greater networking activities of small innovative firms (Docter and Stokman 1987; Rothwell 1991).
NF-κB activation is accompanied by nuclear translocation and upregulation of DNA binding activity.
NF-κB binding activity was also increased markedly.
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