Sentence examples for binding activity of target from inspiring English sources
In addition, rs11614913 T>C was shown to be associated with lung cancer risk, through altering the expression of mature miR-196a and binding activity of target mRNA [5].
They found that the rs11614913 SNP in miR-196a2 is associated with increased risk and shortened survival time of non small cell lung cancer as it alters the expression of mature miR-196a and the binding activity of target mRNA.
The experiments confirm specific binding activity of the target peptide (QPIHPNNM) to dysplasia in comparison to hyperplastic and normal colonic mucosa and to the control peptide (GGGAGGGA) on a microscopic scale.
Although the FadR picture seems relatively complete right now, the residues other than direct DNA-binding sites remain unclear that contributes significantly to the binding activity of FadR to target promoters.
It is therefore possible that CCA1 protein is post-transcriptionally modified only in Cold/Light by a CKII kinase induced phosphorylation, which has been shown to stimulate the binding activity of CCA1 to the target DNA regulatory regions [ 48, 49].
We also tested the DNA binding activity of CREB, another downstream transcriptional target of activated ERK1/2.
CBP-mediated acetylation increases the nuclear retention and the DNA binding activity of HNF4α, which increases the target gene activation by HNF4α [ 31].
To determine the binding activity of miR23b on consensus sequence of target gene, NOX4, in injured spinal cord tissue, NPC cells were seeded in six-well plates until 70% confluence and pUHG-miR23b was transfected using Lipofectamine LTX and Plus Reagent, referring to the manufacturer's protocol (Invitrogen).
These changes were associated with decreased Notch-1 expression and DNA binding activity of NF-kappaB and its target genes such as Cyclin D1, Bcl-2, and Bcl-xL.
The peptide ELISA was used to describe the binding activity of scFv anti-p17 to its target peptide (p17.1) and four mutant peptides (p17.3, p17.7, p17.8, and p17.9).
