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(A ) DNA binding activity of different Elba protein variants.
As such zebrin may be regarded as a biomarker linking different cerebellar cortical zones, potentially binding activity of different olivo-cerebellar modules and mossy fiber systems (Voogd and Ruigrok, 2004; Pijpers et al., 2006; Ruigrok, 2011).
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In this research, we designed a group of duplex DNA substrates containing specific origin recognition boxes (ORBs) of the archaeon and identified the DNA-binding activities of different SsoCdc6 proteins.
There are similarities and subtle differences in how USP7 contributes to the DNA binding activity of these two very different proteins.
The binding activity of e20 against the different genotypes was then expressed as percentage of the reactivity observed on genotype 1a (relative binding activity), measured by sorting for each genotype the number of cells featuring a higher fluorescence signal than cells without Fab.
In total, the residual DNA binding activities of 15 different TFs were estimated against a panel of inhibitors that could be broadly classified into "Keggin", "Dawson" and "simpler polyanion" (metatungstate, sodium molybdate and decavanadate) types.
Although it is well known that the core IL-8 promoter contains binding sites for AP-1, C/EBP and NF-κB, the different binding activity of AP-1, C/EBP and NF-κB on the IL-8 promoter has been attributed to different IL-8 production in the cells [ 37, 42].
Extensive biophysical studies indicate that the hyperstable substitutions enhance the binding activity of mutant p16 through several different mechanisms, including an increased amount of secondary structure and thermostability, reduction in exposed hydrophobic surface(s) and/or a reduced tendency to aggregate.
To demonstrate the ECM binding activity of α-DG derived from different thymocyte populations, binding to laminin was assessed by overlay assay.
To visualize the effect of NTD125 on the DNA binding activity of p53, recombinant NTD125 in different amount (as shown in figures) was added to the p53 and incubated for 1 hour at 37°C prior to set the reaction.
These findings suggest that mechanistically IS3 blockade is not conflicting with ATP-pocket binding activity of TKIs, but functions through a different pathway.
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