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Indeed, we found the minor shifts in the plasminogen binding activity of both encapsulated and stationary phase cells to be quantitatively similar.
The erythrocyte binding activity of both 220 kDa and the 80 kDa fragments was confirmed by PfRH2a/b antibodies raised against rPfRH240 and rRH2-Pro1.
The analysis offered two uncorrelated factors: the first factor explains 87.29% of the variance and correlated with the average of the binding activity of both TIR1 and AFB5 with r = −1.0 (Factor 1 = Efficiency).
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To analyze the transmembrane TNF-α binding ability of h357, we transfected an uncleavable form of transmembrane TNF-α cDNA into NS0 cells to express it on the cell surface, and used flow cytometry to assess the binding activities of both m357 and h357 IgGs.
This structure is essential for the stability and DNA-binding activity of both proteins.
Next, ChIP assays revealed that SRT2183 reduces the DNA-binding activity of both NF- κB and STAT3 to the promoter of GADD45G, which is one of the most upregulated genes following SRT2183 treatment.
In fact, it has been reported that treatment of human erythroleukaemia K562 cells with an NO+ donor decreased the RNA-binding activity of both IRP1 and IRP2 (reviewed by Ref. 75).
The ability of DOX to modulate the RNA-binding activity of both IRP1 and IRP2, and hence the expression of IRE target genes, could be involved in both the antitumour and cardiotoxic properties of the drug, and has produced some important clinical results.
Furthermore, to investigate the intracellular DNA binding activity of activator protein (AP -1.
Downregulation of uPAR and cathepsin B also retarded nuclear translocation and interfered with DNA binding activity of CREB in both U251 and 5310 cells.
As expected, inS3-54 inhibithethe DNA-binding activity of STAT3 both in vitro and in situ.
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