Sentence examples for binding activity is inhibited from inspiring English sources

Interestingly, its mRNA binding activity is inhibited by the binding of ATP molecules that compete for the same protein domain [48].

In human endothelial cells, its location on the membrane is affected and its GTP binding activity is inhibited by a high concentration of mevastatin (10 μM) [ 31].

This follows from the recollection that AtCPSF30 is a calmodulin-binding protein, and its RNA-binding activity is inhibited by calmodulin in a calcium-dependent manner [28].

8 mTORC1 is able to form a complex with multiple binding partners, and its activity is inhibited by rapamycin and related drugs including temsirolimus/CCI-779, everolimus/RAD001, and ridaforolimus/AP23573.

Beclin-1 is an essential component for activation of autophagy, and its autophagy-promoting activity is inhibited by binding to an anti-apoptotic protein, Bcl-2 [ 39].

Pak2 catalytic activity is inhibited by binding of two α-helices in the AID (residues 111 131) to the G-helix, and the kinase inhibitory segment (KI, residues 136 149) to the active site cleft [17] [19].

In one of them, including only some modified β-lactamases, the enzymatic activity is inhibited upon ligand binding and it seems to be caused by the steric coverage of the active site by the bound antibody.

Src activity is inhibited by the binding of RACK1 but RACK1 can transport Src to specific cellular compartments where Src can function.

On one hand, GD3S activity is inhibited by the binding of A β peptides to GM3, consequently reducing substrate availability and preventing the conversion of GM3 to GD3.

ILK kinase activity is inhibited by interaction with its binding partner, α-parvin.

It has been suggested that TNFα-induced NF-κB activity is inhibited by optineurin due to its competition with NEMO for binding to ubiquitinated RIP [19].