Sentence examples for binding activity can be from inspiring English sources

Induction of AP-1 DNA binding activity can be achieved by activation of pre-existing Fos/Jun proteins or through induction of de novo protein expression [ 40].

However, we demonstrate that metal binding activity can be reintroduced into the putative active site by mutagenesis.

Our results indicate that not only a positive cooperativity but also a context-dependent reduction in the DNA binding activity can be induced by assembling zinc finger modules.

Ku DNA ends binding activity can be detected easily by using double-stranded DNA fragments in an electrophoretic mobility shift assay (EMSA) as previously described [27], [39].

We also show that the DNA binding activity can be inhibited by the tumour suppressor p53 and suggest that this may prevent genome destabilizing events such as HR between non-homologous sequences.

Although TREM2 binding activity can be detected on macrophages (Hamerman et al., 2006) and microglia (DS Davis and MJ Carson, unpublished data) by flow cytometry, TREM2 binding activity by IbaI+ microglia was only rarely detected by immunofluorescence in tissue sections.

The binding activities can be obtained experimentally, while the probability of conformations in solution can be computed.

It serves for the engineered display of specific peptide sequences, but will also allow the construction of random peptide libraries from which specific binding activities can be recovered by affinity selection.

However, the lysine mutants bound POPS/POPC liposomes like the wild-type C2C domain, suggesting that different residues mediate phosphatidylserine and phosphatidylinositol binding and that that these binding activities can be selectively abrogated.

RelB DNA-binding activity can be stimulated by RANK and LTβR, two receptors coupled to NF-κB activation and shown to be important for thymic medulla and lymphoid organ formation [39].

The present work also showed that porphyrin binding and catalytic activity can be separated to some extent; N-terminal deletion of 565 residues (42% of the sequence) from the Synechocystis ChlH abolished enzymatic function, leaving porphyrin binding unaffected.