Sentence examples for binding activity as an from inspiring English sources

However, in pull-down assays the flag-tagged 37 kDa fragment remains associated with the other proteolytic fragments, and the fragments retain the same level of motor domain and Hsp90 binding activity as an equivalent amount of undigested Unc45bFlag.

These four fragments remained associated with the Flag-tagged 37 kDa fragment in the pull-down assay, and they retained the same level of motor domain and Hsp90 binding activity as an equivalent amount of undigested Unc45bFlag.

However, we and others have used a fusion protein composed of the extracellular domain of TREM2 fused to the Fc region of human IgG to detect TREM2 binding activity as an assay of putative TREM2 ligand(s) expression (Hamerman et al., 2006).

20-hydroxycholecalciferol inhibits the activation of NFκB DNA binding activity as well as NF-κB-driven reporter gene activity in keratinocytes.

Similar to what observed with FadRK113 mutant protein, other two mutant FadR proteins with single mutation of either F74G (Fig. 6D) or W75G (Fig. 6E) did not exhibit DNA binding activity, as well as the FadR mutant with the double point-mutations of F74G plus W75G (Fig. 6F).

Moreover, the level of overall P-GTP binding activity as well as the amount of Rho-GDI protein is elevated in tumorigenic tissue, notably yet to a much lower extent than Rho proteins.

Flii colocalizes with actin and microtubule-based structures, is required for normal actin distribution, and possesses Ca2+-independent G-actin binding activity as well as F-actin binding and severing activities [ 3, 6– 8].

The multi-target miRNAs have a total of 528 different mRNA targets, which are involved in a variety of functions, but there is a notable over-representation of proteins with transcription factor activity and receptor binding activity as well as involvement in developmental processes (false discovery rate < 0.001, see Additional file 2).

This indicated that by using the octamer binding activity as a reference there were no major alterations in Pax-5 DNA binding in the course of SK-BE(2 c differentiation.

To determine whether this is the case, and indeed the value of using the DNA binding activity as a functional screen, each of these have been changed to their respective mutations, and also to glutamic acid and alanine, by Quik change site-directed mutagenesis.

They all share a HIN200 domain that confers DNA-binding activity, as well as a pyrin domain that can associate with other pyrin-containing proteins to enable assembly of an inflammasome.