Finally, this work provides a structural basis for the role of an Fe S cluster domain in the DNA-binding activity and stability of AddAB, and reveals an unexpected structural similarity with the DNA glycosylase EndoIII.
CBFβ is indispensable for Runx1 activity in cells of the hematopoietic lineage because of its role in enhancing the DNA-binding activity and stability of Runx1 proteins (Adya et al., 2000).
CSD possesses nucleic acid binding activity and is capable of binding to single-stranded DNA/RNA and double-stranded DNA19.
These rearrangements often result in changed binding properties, activity and stability, and subcellular localization of a protein [ 4, 19].
We also describe our continuous efforts in achieving a label-free detection without non-specific binding while maintaining the activity and stability of immobilized biomolecules.
Experiments with this unique probe demonstrated that α-exosite binding enhanced both catalytic activity and stability of the LC.
Cofactor binding, activity measurements, storage stability, and ability of the nanoparticle-immobilized TbADH-NADPH bioconjugates to synthesize chiral alcohols with high enantioselectivity using 7-hydroxy-2-tetralone as substrate were also studied.
As mentioned, MT may participate in regulating p53 stability and DNA-binding activity, and in protecting cells against cadmium-induced toxicity, p53-induced reactive oxygen intermediates, and apoptotic DNA damage.
Using group I permuted-intron-exon sequences, circular forms of the HDV ribozyme, the RNA component of RNaseP from B. subtilis, the HIV TAR and a short HIV Rev-binding element were generated and tested for activity and stability.
Herein we identify formate binding strength as a key parameter limiting the activity and stability of known catalysts for methanol synthesis in the presence of CO2.
