Sentence examples for binding activity and is from inspiring English sources

We show that the CXXC domain of Tet1 has no DNA binding activity and is dispensable for catalytic activity in vivo.

Phosphorylation of L-plastin on residue Ser5 increases its F-actin binding activity and is required for L-plastin-mediated cell invasion.

Most importantly, we have demonstrated for the first time that the processed form of PfRH2a/b possesses erythrocyte binding activity and is involved in sialic acid independent invasion.

This was not surprising to us, as Hmt1 has no reported DNA binding activity and is likely to associate within the proximity of the DNA via its interaction with DNA-binding proteins.

A scFv is the smallest antibody fragment which retains full binding activity, and is a common component of many bispecific antibody formats, e.g., BiTEs (Bispecific T-cell Engager) and DARTs (Dual-Affinity Re-Targetting).

While the former is highly cytotoxic, has high DNA binding affinity, and localizes to the nucleus in wildtype breast tumour cells, doxorubicinol is over a million times less cytotoxoic, has significantly reduced DNA binding activity, and is retained in the cytoplasm or lysosomes of cells.

The CXXC motif was shown to have a zinc binding activity, and was suggested to maintain a stable conformation of the catalytic transglutaminase domain that is required for deglycosylation activity [18], [22].

Both possess ATPase and protein and nucleic acid binding activity and are involved in many biological processes, including chromatin remodeling, transcription regulation, ribonucleoprotein complex biogenesis, nonsense-mediated mRNA decay, and the DNA damage response.

A-6, which was evolved from CBM4-2 and selected, using phage-display, for its ability to recognize Avicel [ 34], and G-4, which was also evolved from CBM4-2 but has no carbohydrate-binding activity and is used as negative control [ 34, 36], were produced in E. coli BL21 λDE3) as previously described [ 34].

Antibody binding activity and specificity were evaluated by ELISA.

This region holds DNA binding activity and can be responsible for protein binding and dimerization [ 34, 35].