Sentence examples for binding activities of several from inspiring English sources

It has been reported that in several injury models, injury leads to significant changes in binding activities of several liver-enriched transcription factors, including HNF4α [ 18- 20].

We have shown that altered levels of SOD2 reveal a sensitivity to oxidative stress created by 2ME2 treatment and result in perturbations in the binding activities of several transcription factors, decreased phosphorylation of VEGFR2, and the alteration of the expression of several genes.

They mainly act by inducing oxidative stress, which activates several proto-oncogenes, like FOS and MYC, and enhances the DNA binding activity of several transcription factors, such as NF-κB and AP-1 [ 5, 6].

Following purification, the binding activity of several scFv antibodies were quantified using a novel Biacore assay.

We report here the use of multiple stabilizing substitutions to increase the stability of p16INK4a and furthermore, to restore Cdk4 binding activity of several defective, cancer-related mutant proteins.

Pituitary hormone prolactin administration directly or indirectly increases the number of proliferating cells during the priming stage of hepatectomy, which causes an increase in the binding activity of several TFs involved in cell proliferation, liver-specific differentiation, and the maintenance of energetic metabolism (Olazabal et al., 2009).

This was followed by further studies on PfRH1 [22] and PfRH4 [24], which mapped the receptor binding region by analyzing the binding activity of several overlapping fragments of the PfRH proteins.

In order to experimentally validate the computational predictions Western blotting experiments of nuclear proteins and EMSA band shift assays were carried out to determine the DNA binding activity of several transcription factors.

Cellular redox potential controls the DNA binding activity of several transcription factors, including NF-κB, AP-1, and p53 [ 53- 57].

Light dependent changes in DNA binding activity of several plant bZIP transcription factors have been shown to involve both phosphorylation and subcellular translocation from cytoplasm to nucleus [ 38].

Since the binding activity of several transcriptions factors such as E-proteins and EBF appear to be modulated during the induced differentiation of neuroblastoma cells [ 5, 22- 24] we wanted to investigate if this was the case also for Pax-5.