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The results revealed that all the polymers exhibited good binding ability with the oligonucleotide (ON).
Among the six small molecules studied, homobarringtonie (shortened as P1), one of the antineoplastic alkaloids separated from Chinese cephalotaxus fortunei, was examined having the highest binding ability with the human telomere G-quadruplex.
Surfactants with carboxylic groups were chosen as the capping agents for the IONPs due to their strong binding ability with the surface atoms of the IONPs, which contributes to the formation of nearly monodisperse nanoparticles with high yield and high stability.
This means a more reasonable result is obtained when considering a methylation effect on transcription factor binding ability with the sense part of model.
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Agarose gel retardation and fluorescent titration by ethidium bromide (EB) showed the strong DNA-binding ability with the Ksv values of 1.21 × 107, 3.76 × 106 and 2.90 × 106 M−1 for the liposomes formed from L1 L3, respectively.
These transcription factor constructs retained their DNA-binding ability, with the six-finger ones being the highest in affinity.
To further characterize the three ΔrgfAC mutant strains, we compared their fibrinogen-binding ability with that of the wild type L1, L2 and L50 strains.
The carbonyl group of amino acid residues has a strong binding ability with metal, suggesting the formation of a layer covering silver nanoparticles and acting as a stabilizing agent to prevent agglomeration in the aqueous medium.
This FT-IR spectroscopic study confirmed that the carbonyl group of amino acid residues has a strong binding ability with silver, suggesting the formation of a layer covering silver nanoparticles and acting as a capping agent to prevent agglomeration and provide stability to the medium.
Thus, we examined whether three prevalent tumor-derived USP8 mutations abolish or reduce USP8 binding ability with 14-3-3ε 14-3-3ε 14-3-3εe candbincrease blocking EGFR degradathen.
Results indicate that the receptor shows the highest binding ability with AMP among studied nucleotides and can selectively and strongly bind nucleotides at neutral medium.
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