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Based on the above results, it seems evident that TBPH maintains NMJ growth and MT organization through futsch protein action and that TDP-43 RNA binding ability plays a crucial role in this process.
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Oxygen migration ability plays a key role in DOSC activities.
Here, we show that ExoI is primarily responsible for this bias and that its ability to be recruited by single-strand DNA binding protein plays a critical role in QPM avoidance and strand bias.
In this paper, we sought to determine whether the change in phosphorylation induced by transcriptional cofactor binding plays a positive or negative role in the ability of Gro/TLE1 to inhibit/delay the transition of cortical progenitor cells into neurons.
Based on the positive correlation between Gro/TLE1 cofactor-activated phosphorylation and ability to inhibit cortical neuron differentiation, we propose that hyperphosphorylation induced by cofactor binding plays a positive role in the regulation of Gro/TLE1 anti-neurogenic activity.
Here we show that the integrin binding glycoprotein CD98 plays a central role in AML.
Instead, substrate binding per se plays a role in reducing ∆G ‡.
The histone acetyltransferase CREB-binding protein plays a key role in regulating the mitochondrial biomass.
The CPMV RNA1-encoded 60 kDa nucleotide-binding protein ('60K') plays a role in the formation of these vesicles.
MBD4 (methyl-CpG binding domain protein 4) was identified as a methyl-CpG binding protein and plays an important role in DNA methylation and carcinogenesis.
RNA binding ability of TDP-43 plays an important functional role in alternative splicing and neurodegeneration [40].
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