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SFN was first identified as a potent inducer of phase 2 detoxification enzymes [8], and studies have also found other anti-carcinogenic as well as anti-oxidant mechanisms including induction of caspases, induction of glutathione S-transferase, inhibition of cytochrome P450 isoenzymes and reduction of the DNA binding ability of nuclear factor-κB [6] [8].
The same nuclear extracts were used to measure the binding ability of nuclear Nrf2 to ARE and showed the same pattern of early peak binding at 30 min (2.1 ± 0.2-fold; p < 0.01) (Fig. 1B).
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In Entamoeba, such S/MARs were found to have reduced binding ability to nuclear matrix compared to the ones that were present outside ORF (our unpublished data).
Briefly, serum was depleted of other heparin binding components before the heparin binding ability of Vn was activated by treatment with urease.
The κ opioid receptor binding ability of these compounds were evaluated with opioid receptors binding assays.
It indicates that the calcium ions can promote binding ability of the C-S-H sample.
The DNA binding ability of Ag and Au NPs were investigated using CT-DNA.
To explore the mechanism underlying the reduction of Hsp70, we measured the levels of Hsp70, cytoplasmic and nuclear heat shock factor 1 (HSF1) in porcine aortic endothelial cells using Western blot, and then further characterized the binding ability of HSF1 and heat shock element (HSE) by electrophoretic mobility shift assay.
The glucose binding ability of the uGRPs was evaluated.
No relationships were observed between serotype and binding ability, or between antibiotic resistance and binding ability of S. pneumoniae.
Analysis of six different heterozygous GATA3 mutations from eight breast tumors has demonstrated loss or reduction of DNA binding ability, aberrant nuclear localization, decrease in transcription activation, and alterations in invasiveness, but not proliferation [ 22].
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