Sentence examples for binding ability as the from inspiring English sources

Since we are interested in drug candidates with a similar binding ability as the statins, we focus on the statin bound HMGR structures.

It is tempting to speculate that LOXL2i-Snail1 interaction prompts Snail1 to adopt a more active conformation with enhanced DNA binding ability as suggested by the DAPA analysis.

We can only speculate that the P1332L mutation increases spectrin binding ability at the SADH2 25aa peptide level, as observed in our binding assay but has the opposite effect in the context of the full length SCRIB molecule.

Electro mobility shift assays (EMSA) were performed to analyze the binding ability as described previously [ 46].

It is therefore not unreasonable to speculate that hMAT2B may also function as a redox sensor by dint of its NADP binding ability, as demonstrated in our structure and solution studies.

Reviewer 3:"To further strengthen the conclusion, you can mutate Asp in TM5 of clade III TAARs (16c or 16f) and introduce Asp back in TM3 and see whether these receptors acquire a ligand binding ability as that of a canonical monoamine receptor type.

The binding abilities as observed by the DB-CoMPP technique were confirmed for all probes and the targeted ligands more precisely defined.

RAGE 143 (Ala23-Thr143) is not only protease resistant but also shows the same ligand-binding ability as that of the full-length extracellular domain.

The substitution of a polar residue at this site in SSIs and most SSIIs may affect their ADPglucose-binding ability as compared to AgtGS and the other SS classes.

We reasoned that, if loss of zinc binding is indeed the sole factor attributed to the decrease in toxicity, Tau*C291H (relative to Tau*C291A) or Tau*C2H (relative to Tau*C2A) may regain zinc-binding ability as histidine residues are also often utilized by proteins to bind zinc.

Putative protein products may have a reduced hormone-binding ability as Exon 10 contains three conserved putative N-linked glycosylation sites (Zhang et al., 1995).