Sentence examples for binders to a specific from inspiring English sources

Since our DRT reference set mainly focuses on strong binders to a specific protein, the low rankings of the target for these two drugs may be partially attributed to their low binding affinities to the target, which are close to the threshold for selecting ligands in our reference set.

High affinity binders to a specific target were obtained from immunized libraries however required a waiting period for suitable immunization to be achieved and an animal care facility [ 11].

Binders belonging to a specific class of VH antibodies [ 8] have been shown to possess a large variability in their capability to refold after heat denaturation.

In addition it is beneficial to include alternative binders in the experimental planning, in case the generation of a binder affine to a specific epitope fails.

So, we were proceeding an alternative way that will be more susceptible to get a high affinity binders to the specific antigen.

Based on an effective interaction between the CIR and the tumor antigen, we demonstrated that combining CIR-mediated activation with FACS sorting of CD69+ T cells, it is possible to isolate binders to tumor specific cell surface antigen, with an enrichment factor of at least 103-fold after two rounds, resulting in a homogeneous population of T cells expressing tumor-specific CIRs.

Repeat proteins are an emerging class of alternative scaffolds for the creation of protein binders to specific intracellular probes.

Pigment is a substance that is dispersed in a binder to give specific physical and chemical properties.

Garber et al.[ 46] propose that in animals, transcription factors exhibit a multilayered architecture: Pioneer factors initiate remodelling of the epigenome, allowing broad binders to prime lineage-specific genes, with dynamic factors facilitating the activation of environment-specific genes.

If you're using more then 1 binder, have a specific colour for each class to keep things more organized.

This repertoire was used for selection of specific binders to different proteins, a hapten, and complex antigens i.e., viral coat proteins, crude snake venom and cancer cell surface.