Sentence examples for bind with the aryl from inspiring English sources

Endocrine disruptors may bind with the aryl hydrocarbon receptor, increasing transcription of CYP1A1 (Behnisch et al. 2001).

DL-PCBs have been the first PCB congeners to be considered in association with endometriosis because, as dioxins, they bind to the aryl hydrocarbon receptor (AhR) and elicit the same spectrum of toxic activities through the same mechanism of action.

PAHs have been shown to bind to the aryl hydrocarbon receptor and affect multiple systems (Nebert and Atlas 1978).

Congeners with no or one chlorine substituent in the ortho positions may assume a coplanar configuration, bind to the aryl hydrocarbon receptor (AhR), and have pattern of toxicity similar to 2,3,7,8-tetrachlorodibenzo-p-dixoin 2,3,7,8-tetrachlorodibenzo-p-dixoin 2,3,7,8-tetrachlorodibenzo-p-dixoin 2,3,7,8-tetrachlorodibenzo-p-dixoin

Dioxins bind to the aryl hydrocarbon receptor (AhR), which, after dissociating from its complex of chaperone proteins in the cytoplasm (including HSP90 and XAP2) translocates to the nucleus.

In rodents, PCBs bind to the aryl hydrocarbon (AhR) and pregnane X receptors (PXR) inducing the expression of catabolic cytochrome p450 enzymes of the CYP1A and 3A families.

PAHs and/or their metabolites may bind to the aryl hydrocarbon receptor (AhR) and accumulate in the nucleus of cells, resulting in increased rates of mutagenesis.

Based on their analyses, the researchers conclude that TCDD and other compounds that bind to the aryl hydrocarbon receptor do not affect sperm creation.

Additionally, dioxin-like PCB congeners can bind to the aryl hydrocarbon receptor, resulting in the induction of the cytochrome P450 CYP1as as well as the UDP-GT isoenzyme UGT1A6 (methyl-cholanthrene-like inducers), which together with UGT1A1 is responsible for the glucuronidation of T4 in rats (Visser et al. 1993).

Upon ligand binding, the AhR binds to the aryl hydrocarbon nuclear translocator (ARNT) protein, resulting in translocation to the nucleus, where the ligand AhR ARNT complex binds to response elements in the promoter of AhR-regulated genes (dioxin response element).

Background: Epidemiological and animal studies indicate that maternal exposure to pollutants that bind the aryl hydrocarbon receptor (AhR) correlates with poorer ability to combat respiratory infection and lower antibody levels in the offspring.