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On the other hand, ferrated siderophores bind with lesser affinity and also exhibit a biphasic binding curve, pointing thereby that the initial bound concentration defines their affinity.
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The authors hypothesised that antidepressants with higher affinity for the serotonin transporter would exhibit greater risk for these outcomes than those with lesser affinity.
IGF-1R is a glycoprotein composed of two extracellular alpha subunits that preferentially bind IGF-1 and IGF-2 and insulin with a lesser affinity.
The mutated domain bound to L. casei NRRL B-441 cells, albeit with a lesser affinity.
HFE binds with transferrin receptor 1 (TfR1), but the C282Y allele has a lesser affinity, allowing TfR1 to bind TF more easily [ 34, 60].
1A and B bind with approximately equal affinity, although the exact affinity could not be obtained as each DNA binds more than one MA.
These analogues bind with extraordinary affinity relative to reactants.
Indeed, dextro enantiomers bind with high affinity σ1 receptor while opposite enantiomers bind opioid receptors.
First, they bind with high affinity and specificity to a wide variety of proteins.
Thus, in this in vitro system, both peptides bind with medium affinity (µM range) to HSC70.
Further characterisation of the recombinant lectin revealed that it specifically binds to the monosaccharide Me-α-galactose presenting, nevertheless, lesser affinity than the native frutalin.
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