Sentence examples for bind with higher affinity from inspiring English sources
Dibenzofuran-4,6-dicarboxylic acid (DDBF) [22] and m-trifluoromethyl-substituted N-aryl phenoxazine (PHENOX) have been explored with the hypothesis that the bulkier tricyclic moieties should bind with higher affinity to the TTR hormone binding pocket [22].
Moreover, the insights from these studies will be valuable for guiding the design and selection of antibody and peptide inhibitors that have larger binding interfaces, and thus have the potential to bind with higher affinity and specificity than their small molecule counterparts.
These long PPS chains (F1 F4) are even more effective with ADAMTS5-2 they they are with ADAMTS5-5 as their favourable increase in Gibbs energy is further increased by their ability to bind with higher affinity to both TIMP-3 and to the multiple binding sites on ADAMTS5-2 [mode (iii)].
Generally, D-4F seems to bind with higher affinity to oxidized lipids containing palmitoyl moiety: PGPC, POVPC, PEIPC and KOdiA-PC.
Ligands with a hydantoin moiety bind with higher affinity than those with other nucleobase-like entities.
Since ADP and NAD+ are up-regulators, they probably bind with higher affinity to the open state.
Here we show biochemically that Hsp70 binds with higher affinity to expanded PABPN1 in vitro, and that binding affinity is proportional to the length of the polyalanine stretch.
They demonstrated that CTLA-4, a homologue of CD28, bound with higher affinity (at least 10-fold) to both B7-1 and B7-2 [37] and inhibited CD4+ T-cell activation.
Five of the 15 nonsteroid lipids in Table 3 were apparently bound with higher affinity by OxP-11D and ten were bound more effectively by D-4F.
