Sentence examples for bind with high specificity from inspiring English sources
Aptamers are modified nucleotides composed of single-stranded nucleic acids that adopt a specific three-dimensional conformation, allowing them to bind with high specificity and affinity to molecular targets in a manner similar to that of monoclonal antibodies.
The ligand patterned surfaces were shown not only to bind with high specificity to anti-DNP immunoglobulin E (IgE), but also to induce specific cellular responses when incubated with rat basophilic leukaemia mast cells [120].
Remarkably, tetrapeptides containing pSXXF motif bind with high specificity and micromolar affinity.
An important component of all of these therapies is the design of antibodies that specifically target specific cancer epitopes, and much of the ongoing research into cancer antibody therapy is focused on the engineering antibodies that bind with high specificity.
This methodology overcomes some of the main obstacles for imaging RNA in live cells since microinjection allows the delivery of the probe to a desired cellular compartment and MBs bind with high specificity to its target RNA without inhibiting its function.
The BSP proteins bind with high specificity to choline-containing phospholipids such as phosphatidylcholine and sphingomyelin present on the sperm plasma membrane [9].
The chlorotoxin (CTx) is a scorpion-derived peptide, which binds with high specificity to glioma cell surface as a specific chloride channel and matrix metalloproteinase-2 blocker.
As shown in Figure 1B and Figure S1, in the presence of Mn2+, Fur dimers bound with high specificity and affinity to PhilD, with an apparent binding constant (KDapp) of about 4.5±1.5 nM, defined as the protein concentration necessary to complex 50% of labeled DNA.
A trimeric complex (nuclear factors YA-C (Y-box binding factors)), forming a highly conserved, ubiquitously expressed transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes.
This complex binds with high specificity to DNA damaged by UV, is absent in a subset of xeroderma pigmentosum group E cells, and is required for global genomic repair of UV-induced damage.
Solution characterization (NMR, UV-vis) of the protein showed that it bound with high specificity to the desired cofactors, suggesting that a uniquely structured protein and well-defined site had indeed been created.
