Sentence examples for bind with greater affinity from inspiring English sources

Finally, the QSAR models were applied to the design of a peptide to bind with greater affinity than the known binding peptide sequences of the yRSP5-1 WW domain.

However, this relationship does not always hold true; cis-permethrin and fenvalerate interact with both closed and open sodium channels, but they bind with greater affinity to the open state (Forshaw et al. 2000; Cantalamessa 1993).

The association of mouse Db heavy chain with monkey β2M is expected since mouse heavy chains bind with greater affinity to human β2M than to mouse β2M, conferring greater stability to the complex [26].

The selective disruption of tumour endothelium by FgnE indicates that this fragment may bind with greater affinity to activated tumour endothelium than quiescent endothelial cells in healthy tissues.

Thus, in response to an AngII infusion in female rodents, AngII will bind with greater affinity for the AT2R than the AT1R.

This showed evidence of allele-specific binding for only one SNP, predicting that BRCA1 binds with greater affinity to the associated G allele of rs1150793 (ACAAGAC) (score 6.4) (relative profile score 90.4%).

Unlike 17β-oestradiol, which displays relatively equivalent binding on both ER subtypes, and raloxifene, which binds with greater affinity to ER-α, genistein aglycone binds selectively to ER-β over ER-α, from 7- to 48-fold, depending on the assay system employed (Kuiper et al., 1997, 1998; Barkhem et al., 1998; Hsieh et al., 2006).

In contrast, NADH binds with greater affinity than NAD+ by a factor of 6 (Table 2).

GBR-12909 selectively inhibits DA uptake and binds with greater affinity to the dopamine transporter than cocaine.

This approach is based on the concept that target DNA that perfectly matches its probes binds with greater affinity than one with a mismatch.

The result was (1) to give a daughter, SUMI-based composome (that bore some similarity to the mother composome) and (2) to release both unbound molecules (that were therefore unprotected and degraded) and a second daughter composome in which the molecules bound with greater affinity to one another than to the SUMIs.