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In mammalian tissues, TFs do not usually act alone but form complexes with other TFs and co-factor proteins, which bind together to the DNA synergistically to affect the transcription of the target genes [ 3].
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Together, these results demonstrate that CTCF associates upstream of the gene promoter in human rDNA and suggest that CTCF and UBF are bound together to the rDNA.
Using re-ChIP, we observed a strong enrichment at the CDKN1A/p21 transcription start site, but not at the MLH1 promoter, clearly indicating that DNMT1 and MBD4 are bound together to the CDKN1A/p21 promoter in 293T cells (Fig. 1C).
Leave enough bag material at the top to bind together to hold the contents in, while allowing the extra bit to give a visual indication of a pumpkin stem.
For instance, proteins bind together to form protein complexes, the physical units that carry out most functions in the cell (Krogan et al., 2006).
C4b and C2a bind together to form C3-convertase, as in the classical pathway, ultimately resulting in the formation of the membrane attack complex (MAC) [ 31].
Pu.1 (Sfpis) is one of only a few genes where all factors bind together to a single cis-regulatory element, the 3′ URE.
In the early 19th century, women wore many petticoats, bound together, to show the great fullness of the skirt.
The two works were bound together to form the manuscript (abbreviated MS) Cotton Tiberius A xiii, now held in the Cotton Library, a collection in the British Library.
Secondly, several thin fibers were bound together to obtain the MMF assembly.
With little real help coming their way, the Ukrainian people have bound together to stand up to the Russian empire, in a David versus Goliath-like fight.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com