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When heparin was added to ECs treated with heparinase I and bFGF, live cell number increased and LDH release decreased significantly compared to heparinase I treatment alone and showed a more pronounced increase in live cells and decrease in LDH than addition of bFGF alone suggesting that bFGF and heparin bind together to prevent HSPG from degradation by heparinase I.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com