Sentence examples for bind to wild type from inspiring English sources
As before, pulldown assays showed that His-tagged γ-tubulin was able to directly bind to wild type GST-NEDD1 CTD protein but the interaction of γ-tubulin with the L642Q mutant was significantly reduced (Figure 5B).
(B ) 1434 RNAs bind to wild type WDR5 but not F266A mutant or vector control.
On the other hand, primer set B cannot bind to wild type allele.
Binding free energies and thermodynamic property differences for nevirapine bound to wild type and Y181C HIV-1 reverse transcriptase were investigated, and the results were compared with available experimental data.
FBXW8 was associated with both cyclin D1 wild type and the T286A mutant, but the majority was bound to wild type, which was mostly phosphorylated at Thr286.
Immunoprecipitation using these mutants revealed NDRG1 specifically binds to wild type and GTP-bound Rab4aQ67L but does not bind to the GDP-bound Rab4aS22N mutant corroborating our in vitro pull-down experiments (Figure 4A).
Simultaneous binding of dasatinib and GNF-5 to T315I caused conformational and/or dynamics changes in Abl such that effects of dasatinib on T315I were the same as when it bound to wild type Abl.
When immunoprecipitation was performed in HeLa cells that were transfected with PLD1 constructs after depleting endogenous PLD1, μ2 bound to wild type PLD1, but not to R304A or R304K mutant (Figure 3B).
10.7554/eLife.03574.016 Figure 5. Lamotrigine binds to wild type but not mutant IF2 in a G-nucleotide-dependent manner.
As we and others reported previously, the percentage of GTP bound to wild type Rap1A is around twenty percent, while Rap1A-V12 is highly GTP-bound [ 13, 32].
