Sentence examples for bind to unique sites from inspiring English sources

The studies described in Figure 3 support a two-site binding model at Smo, whereby SAG and purmorphamine bind to unique sites on the receptor.

Each was sixty nucleotides long and tested by BLAST analysis to bind to unique sites in the Group II C. botulinum Eklund 17B (NRP) chromosome and plasmid sequences.

Epothilones, discodermolide, eleutherobins, and sarcodictyins compete with paclitaxel for binding to microtubules and bind at or near the taxane site, whereas laulimalide seems to bind to unique sites on microtubules.

These studies revealed that a large class of HDs, including Slou and Msh, predominantly recognize TAAT core sequences but that each HD also binds to unique sites that deviate from this canonical motif.

Our results do not distinguish between the two possibilities that lipid A and daunorubicin bind to unique allosterically linked sites, or to overlapping sub-sites within a large substrate-binding pocket.

Additionally, peptide substrates may diminish the ability to detect inhibitors that bind to docking sites of a native protein substrate or that bind to unique conformational states induced by protein substrate binding [ 12].

First, a subset of +TIPs preferentially bind to unique structural features present at the plus end vs the body of the microtubule, and can recruit additional proteins to these sites.

However, most antibodies do not bind to unique epitopes and so they will cross-react.

Interestingly, the FH1 N-terminal PxxP motifs seemed to bind stronger to the unique site-containing SH3 domain construct since the reporter gene activity determined for clones S433 and S010 exhibited a significant increase only for TK3-US-SH3, but not for TK-SH3.

We have used a structure activity approach and biophysical methods to characterize a class of inhibitors that bind to a unique allosteric site within the C-terminus of HSP70 and DnaK.

Using a yeast-two-hybrid screening system, Bakkers et al. found that two modifying enzymes, the E3 ubiquitin ligase Nedd4 and the SUMO-conjugating enzyme Ubc9, bind to distinct sites in the unique C-terminal region of ΔNp63 α.