Sentence examples for bind to unique epitopes from inspiring English sources
However, most antibodies do not bind to unique epitopes and so they will cross-react.
Only antibodies that will bind to a unique epitope will react specifically to its intended target protein.
Like trastuzumab, pertuzumab is a HER2-targeted humanized monoclonal antibody; however, it binds to a unique epitope in the dimerization domain and has a complementary mode of action to trastuzumab [ 8, 9].
This mAb binds to an unique epitope on HBsAg and potently suppress levels of HBsAg and HBV DNA for several weeks in HBV transgenic mice (Zhang et al., 2016).
They bind to three distinct epitopes: epitope I (1a2y and 1jhl), epitope II (1p2c and 2iff) and epitope III (1j1x) (see Supplementary Section 5).
As a test case we have picked lysozyme and the five distinct antibodies that bind to three different epitopes: epitope I (1a2y and 1jhl), epitope II (2iff and 1p2c) and epitope III with 1j1x (see Supplementary Section 5).
Prototypic Cluster A mAbs A32 and C11 bind to similar epitopes on gp120 but only weakly cross-compete with each other, suggesting they have unique specificities (Guan et al., 2013).
When the antibody is mono-specific to one defined and unique epitope, one has to take into account that such an antibody will still bind to similar epitopes albeit at lower affinity.
Should pathogenic anti-LGI1 antibodies bind to specific epitopes, these epitopes could be druggable and lead to effective new epilepsy treatments.
