Sentence examples for bind to two distinct from inspiring English sources

This is further supported by our modeling studies, showing that NeoR6 and CXCL12 bind to two distinct sites on CXCR4, in contrast with other CXCR4 inhibitors, e.g. T140 and AMD3100.

Ang II possesses the capacity to bind to two distinct receptor subtypes, AT1 and AT2 [45].

The ET family consists of three isopeptides, ET-1, ET-2, and ET-3, which bind to two distinct subtypes, ETAR and ETBR, of G protein-coupled receptors [20].

Or, this percentage is within the range of cells expressing two TCR alpha chains that could bind to two distinct tetramers via two distinct TCRs.

Notably, the benzimidazole scaffold is another known privileged structure, providing an explanation for why CF15 and CF18 bind to two distinct sites in PHD HD1 to its benzothiazole cleft and its K4me pocket.

The latter case is critical when drug is able to bind to two distinct membrane receptors, becoming a ternary system that additionally requires an average distance between receptors to be considered.

To mediate its immunosuppressive function, CD73 generated adenosine can bind to four distinct G-protein-coupled receptors: A1, A2A, A2B, and A3.

They bind to three distinct epitopes: epitope I (1a2y and 1jhl), epitope II (1p2c and 2iff) and epitope III (1j1x) (see Supplementary Section 5).

H-NS binds to two distinct sites and forms a bridge structure to block the binding of RNA polymerase (RNAP) to a promoter or trap RNAP in an open complex at a promoter, thereby inhibiting transcriptional elongation.

Among 1,732 MTLs, ≈45.9% ligands (795 entries) were bound to two distinct proteins (Figure 2E), which was lower than the result (65%) reported by Noé Sturm et al. [19].

Moreover, Ubvs that bound to two distinct sites on the intracellular adapter Grb2 could be combined to generate a potent inhibitor that functioned in cells.