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Exact(7)
We provide biochemical data to support the notion that ΔNp63 can bind to this element both by EMSA and ChIP experiments and that all three isoforms of ΔNp63 can induce K5 when ectopically expressed, thus confirming that K5, similar to its partner K14, is a direct transcriptional target of ΔNp63.
TTP could bind to this element as well as to the TNF-α ARE.
The TF-A gene incorporates a TF-RE, and when homodimers bind to this element, TF-A transcription is increased.
It is possible that estrogen receptor α can bind to this element in hTERT promoter and then activate hTERT transcription (Kyo et al. 1999; Misiti et al. 2000).
Chromatin immunoprecipitation (ChIP) assay revealed that both sublytic C5b-9-induced IRF-1 and overexpressed IRF-1 by using pEGFP-N1/XAF1 could bind to this element.
Curiously, however, chick FOXD3 does not bind to this element, at least in vitro; rather, its repressive activity comes about by a mechanism that is independent of DNA binding.
Similar(53)
While Nrf2 was incapable of binding to HepcARE on its own, MafG homodimers bound to this element.
This sequence, C/T TAA C/T NGCT (N168), was predicted to be a novel transcriptional element but no transcription factor has yet been identified which binds to this element.
Lutterbach et al. found that p21 WAF1 promoter contains three putative RUNX-binding sites and the proximal element is required for the downregulation of p21 WAF1 in NIH3T3 cells, indicating that RUNX2 directly binds to this element and thereby reducing p21 WAF1 expression.
A specific protein called repressor element silencing transcription factor (REST), also known as neuron-restrictive silencing factor (NRSF), binds to this element and prevents the expression of these genes in non-neuronal cells (Seth and Majzoub 2001; Belyaev et al. 2004).
The Rev molecules change shape when they bind to the element, and specific regions of the element were found to be important for this.
More suggestions(17)
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bind to this probe
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bind to this substrate
bind to this channel
bind to this kind
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bind to this enzyme
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