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As C. elegans DAF-16 and its mammalian homologs bind to this consensus DBE, the presence of the DBE in Ac-DAF-16 selected hookworm genome fragments suggests a conserved function for hookworm DAF-16.
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Stat1, Stat3, Stat4, and Stat92E all bind to this generalized consensus site [ 34, 35].
Electrophoresis mobility shift assay (EMSA) further demonstrated that AnCrpA could bind to the consensus CRP binding site in E. coli [ 27].
Under certain conditions, NF-κB can also bind to the consensus sequence of the Sp1 binding site, thereby competing with Sp1 [61], [61].
Ac-DAF-16 was previously shown to bind to the consensus DBE sequence and initiate reporter gene transcription [17].
They recognize and bind to the consensus DNA sequence CTA(A/T 4TAG/A as homo- or heterodimers via a 56-amino acid domain (i.e. MADS-box) [7], [8].
WRKY proteins are generally considered to bind to the consensus W-box sequence TTGAC(C/T) [ 30].
Three degenerate capture oligos (M01, M02 and M03) were designed to bind to the consensus M gene sequence region of influenza A virus.
Our data are consistent with the notion that Myc, when bound to this particular consensus, participates mainly to transcriptional activation.
In this bimodal model, the RAR-RXR dimer binds to the consensus DNA sequences, including the DR5 or DR2 motif, in which ligand induction is through the RAR, whereas RXR is generally considered a silent partner [ 6].
In summary, nvp63 bound to the consensus DNA sequence recognized by hup53 and transactivated target gene transcription in vitro.
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