Sentence examples for bind to these sites from inspiring English sources

Intracellular proteins containing Src homology 2 (SH2) or phosphotyrosine binding (PTB) domains bind to these sites of tyrosine phosphorylation [2], initiating a wide variety of signaling cascades including the Ras/MAPK, PI3K/Akt, PLCγ/PKC, and Stat pathways [3].

Quenching of the fluorescence of the lipid-exposed Trp residues in wild-type KcsA by BrSA shows that BrSA can also bind to these sites with a binding constant relative to DOPC of 0.67 ± 0.04.

Given the evidence that both 12 0 and 12 5 function as TF binding sites, these findings suggest that the proteins that bind to these sites may also bind to each other, or even prevent each other from binding.

Two putative HoxD13 binding sites, the HoxD13 binding site 1 (-667): gttct and the HoxD13 binding site 2 (-477): ctagg were identified, suggesting that Hoxd13 could directly bind to these sites to regulate Gli3 expression (Fig. 7).

Instead of targeting the PHGDH active site, we computationally identified two potential allosteric sites and virtually screened compounds that can bind to these sites.

These results suggest that the separation between all three elements is significant for the interaction or discrimination of the transcription factors which bind to these sites.

It is possible that AdpA binds to these sites cooperatively with some other DNA-binding protein in vivo (see Discussion).

Here, we demonstrated that a number of the ripening-associated genes contain these typical binding sites in their promoters and that RIN actually binds to these sites.

Brain spectrin binds to these sites better than erythrocyte spectrin suggesting that erythrocytes have residual binding sites for nonerythroid spectrin.

Mutagenesis studies indicated that the function of the promoter was dependent upon synergistic interactions between transcription factors bound to these sites.

When bound to these sites, which are referred to as benzodiazepine receptors, it modulates the effect of GABA A receptors and, thus, GABAergic neurons.