Sentence examples for bind to their sequence-specific from inspiring English sources

PPARs dimerize with RXRs to bind to their sequence-specific target sequences.

As long as the target protein is abundant in the cell it produces sufficient numbers of such oligomers which bind to their specific GA-sequences and, thereby, inhibit locally the transcription of the target protein in the associated loop.

The C/EBPs together form a highly conserved family of transcription factors that bind to sequence-specific DNA sequences as dimers and that regulate the transcription of genes involved in proliferation and differentiation.

Intriguingly, a structure of ADAR2 bound to RNA displays sequence-specific contacts between the protein and the minor groove [ 29].

The complexes then bind to sequence-specific DNA, which can condense the chromatin structures and repress gene expression [ 27].

Furthermore, mp53 extracted from heated cells came to bind to the sequence specific region after heating combined with glycerol pre-treatment.

p53 is a transcriptional activator that binds to sequence-specific binding sites at the promoters of several cellular genes and activates their transcription.

PPAR α binds to sequence-specific target elements as a heterodimer with the retinoid X receptor (RXR).

55 The homeodomain binds to sequence-specific DNA motifs and regulates the transcription of genes relevant to the formation of specific segmental architecture.

Taken together, our data suggest that the fungal CSL proteins may adopt the CSL fold and we further show that these proteins posses notably conserved regions of functional significance related mostly to their ability to bind DNA in a sequence-specific manner.

These changes permit the ER α complexes to bind sequence-specific oestrogen response elements located in the regulatory regions of oestrogen target genes, thus controlling their level of transcription.