Sentence examples for bind to the unique from inspiring English sources

All amide moieties of the bengamide derivatives bind to the unique shallow cavity and interact with a flat surface created by His-212 of MtMetAP1c in the Mn II) form.

Regulatory proteins bind to the unique carboxy termini of the PP1 isoforms to direct their isoform specific activities.

This led us to propose that in HydG a tyrosine-derived fragment (perhaps DHG) could bind to the unique iron of the three-cysteine-coordinated cluster housed in the C-terminus (see Figure 7).

Here, we report that ethaselen, a novel organoselenium compound with anticancer activity, specifically binds to the unique selenocysteine cysteine redox pair in the C-terminal active site of mammalian TrxR1.

The C-cluster instead depicts a H2O/OH− molecule bound to the unique Fe.

The resulting native structure shows H2O/OH− bound to the unique iron of the C-cluster and no bridging sulfide, despite the absence of CO.

In our native structure, a positive Fo − Fc electron density peak greater than 4σ is present, indicating a ligand bound to the unique Fe of the C-cluster.

It has previously been reported that Nck binds to the unique domain of Lck via its SH3 domains, and that phosphorylation of Ser disrupts the interaction [ 23].

Further, a base may not be necessary for the first deprotonation, as the p Ka of the water molecule may be dramatically lowered in its distinctive environment, bound to the unique Fe of the C-cluster.

The reduced [4Fe 4S]+ cluster can transfer one electron to SAM to homolytically cleave the S C(5′) bond, generating methionine (still bound to the unique iron) and a dAdo.

Although it is difficult to unambiguously prove that a ligand is a H2O/OH− molecule using crystallography, our assignment is consistent with electron−nuclear double resonance (ENDOR) studies of MtCODH, which indicated that H2O/OH− binds to the unique Fe (40).