Sentence examples for bind to the toxin from inspiring English sources
It can bind to the toxin, preventing cleavage, so the toxin cannot enter cells.
Unfortunately, this can raise the BoNT-detection limit, depending on where the antibodies bind to the toxin.
TA modules are defined as protein pairs consisting of a toxin and its antitoxin; the antitoxin can bind to the toxin and neutralize its toxic effects [3].
Similarly, full-length CSPG4 protein co-precipitated with TcdB, whereas the CSPG4 protein lacking amino acids 30-640 (CSPG4ΔN30-640) losthehe ability to bind to the toxin.
The modular nature of antitoxin protein wherein the N-terminus has the DNA-binding motif, whereas the extended C-terminus binds to the toxin groove, facilitates such multiple antitoxin partners.
Diphtheria toxin consists of an A-fragment that inactivates elongation factor 2 and a B-fragment that both binds to the toxin receptor and mediates translocation of the A-fragment across cellular membranes to the cytosol.
The cognate antitoxin (RNA or protein) binds to the toxin and blocks its activity [ 26].
The antitoxin binds to the toxin via its C-terminus, which is unstructured or partially unstructured in toxin-free state (Nieto et al. 2007) but adopts an extended structure on binding to the toxin.
Melibionic acid thus bound to the toxin primarily through interactions made by the galactose residue while the gluconic acid provided non-specific interactions that enhanced the affinity relative to free galactose.
When no PSP toxins were present in the sample, the binder was then free to bind to the immobilised toxin producing a response (Campbell et al. 2007).
In order to develop this technology, the aim of this present study was to identify scFvs which can simultaneously bind to the tetanus toxin heavy chain C-terminal sub-domain (Hc), characterise their bio-physical properties and determine their functional efficacy.
