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Although in our study, the selected peptide was unable to bind to the stem cell line of the other species, further proves its specificity, we still observed that several peptides with "homologous core sequence", namely the PWX (L/V) motif, were able to bind to differentiated ES cells, albeit with low efficiency.
It has been reported that TLS preferentially bind to the stem loop structure [ 7, 14].
Additionally, other studies also suggested that a vigorous antibody response to pH1N1 vaccination resulted from the activation of preexisting memory B cells, which did not only bind to the stem region but also the head region of HA [ 39].
Some of these antibodies bind the HA stem region of H1, H2, H5, H6, H8, H9, H11, H12, H13, H16 influenza A viruses and others bind to the stem region of most of group H3, H4, H7, H10, H14, H15 influenza A viruses.
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A second explanation is that this binding is weak and does not survive gel resolution in binding shift assays; (3) hnRNP H was seen to directly bind to the stem-loop IDX-rasISS1 that involves a dsRNA stem-loop structure (Figure 2E, lanes 4 9); and (4) p68 regulates hnRNP H-stem-loop binding since p68 reduces this interaction (Figure 2E and 2F).
This RNA can be visualized by expressing the YFP-MS2 binding protein, which binds to the stem loop structure of the MS2 translational operator as a dimer (Fig. 1A). 3 hours after activation, YFP-MS2 accumulates at the transcription site in 88.3±1.8% of cells (Fig. 1B, panel k; Fig. 1C; Table S1).
These proteins include the antigen receptors of lymphocytes, the (MHC) proteins, the coreceptors involved in cell-to-cell recognition in immune reactions (such as the receptors named CD4, CD8, and CD28), and the FC receptor that binds to the stem of the Y-shaped immunoglobulin molecule.
Specifically, we have shown that siRNA mediated inactivation of MBNL1, which binds to the stem of the CUG hairpin, results in increased dispersion of nuclear foci in DM1 cells [46].
One reason for the inverse relationship between morphology and form-meaning compositionality is that inflections such as affixes are, by definition, phonologically bound to the stem, which increases opportunities for phonological compression and sound change to disrupt regular mappings between form and meaning.
The results are consistent with our idea that the peptide preceding the DUF1115 domain binds to the stem II portion of U4/U6 di-snRNAs.
This cytokine receptor is expressed on the surface of hematopoietic cells and binds to the stem cell factor (also known as c-Kit ligand).
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