Sentence examples for bind to the specific from inspiring English sources
These two molecules (Table 1, Additional File 1 and Figure 1) bind to the specific cytosolic binding-protein FKBP12; but while tacrolimus complexed to FKBP12 inhibits the Ca2+-dependent phosphatase calcineurin, rapamycin-FKBP12 binds to and inactivates mammalian target of rapamycin, a pivotal regulator of cell growth and proliferation for many cell types.
The result showed that NLP7 could bind to the Q4-3 and Q4-4 regiofs of NRT1.1 promoter in vitro (Fig. 5d), implying that NLP7 may bind to the specific regions of NRT1.1 promoter.
The receptor molecules on the second neuron can only bind to the specific neurotransmitters released from the first neuron.
To our interest, mutations of five conserved residues located within these two region had almost completely lost their ability to bind to the specific target DNA attB.
Moreover, no complexes were seen in the gel retardation experiment with DNA attP for mutants G182A/F183A and C374A (Fig. 5B), indicating G182A/F183A and C374A had completely lost their ability to bind to the specific target DNA attP.
Results of DNA binding activity assays showed that mutants (R18A, I141A, L143A, E153A, I432A and V571A) exhibited a great decrease in DNA binding affinity approximately 1 6 fold, and mutants (G182A/F183A, C374A, C376A/G377A, Y393A and V566A) had completely lost their ability to bind to the specific target DNA attB as compared with wild-type protein.
It has a DNA binding domain (BD) that binds to the specific sequence upstream of the GAL4 regulated genes and an activating domain (AD) which binds to other proteins to activate the transcription.
Despite the divergent domain organizations and sequence identities, the TFs characterized to share a significant degree of structural similarity of the DNA-binding domain (DBD), which binds to the specific DNA region [ 5].
ADCC is induced when mAb binds to the specific antigen on the surface of malignant cells followed by binding of the Fc domain of the mAb to the Fc receptors on the surface of effector cells.
In conclusion, analysis of genomic DNA for CK19 suggested that expression of mRNA for CK19 was regulated by several transcription factors which bound to the specific sequence with the promoter region of the CK19 gene.
