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This result differs with that found for the equivalent mutation (S395T), in the closely related tyrosine hydroxylase, which had no effect on substrate Km, showing that while the architecture of the two active sites are very similar the amino acids that bind to the respective substrates are different.
By utilizing self-assembly to bind to the respective receptor regions, a chemical reaction is instigated, causing the molecule to undergo conformational changes.
Following the manufacturers instructions, we seeded 1×105 cells suspended in DMEM (100 µl) onto the coated ECM-substrates and analysed for the cells ability to bind to the respective ECM proteins using a fluorescence plate reader (485/530 nm).
One major cytokine axis involves the microenvironmental expression and secretion of stromal cell-derived factor-1 (SDF-1) and CXCL13 which bind to the respective cytokine receptors on CLL cells, promoting migration and survival in CLL cells.
The D. mojavensis and D. ananassae ancestral proteins appeared to bind to the respective TIRs slightly better than the corresponding consensus sequences.
The Gal4-VP16 acthereforethexistse, exintwoin two states: an inactive state, where the transcriptional activator is located at the membrane and where it cannot bind to the respective operator site, and an active state, where the Gal4-VP16 is translocated into the nucleus where it can bind to and activate the selected effector gene (e.g., reporter or human IFN-β1).
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Chloroquine was found to protect DNA from degradation and enhance transcription of DNA bound to the respective carriers.
Industry solutions like Akitio MyCloud[9], mydlink Cloud[10], Synology Cloud Station[11] and LenovoEMC Personal Cloud[12] as well as Samsung HomeSync[13] and myQNAPCloud[14] have not been considered as they are proprietary, focussed solely on storage service and are bound to the respective companies' storage devices.
After three rounds of selection, single phage clones that bound to the respective mAb and not to the isotype-matched control mAb in phage ELISA were subsequently subjected for DNA sequencing.
The value of r has similarly been normalized r = (rp−br)/rmax where rp is the measured fluorescence intensity of the rebinding species, br the background signal, and rmax the fluorescence intensity when only the 'rebinding' species (e.g. CaM-A647 in complete absence of CaM-A488) is bound to the respective peptide under otherwise identical experimental conditions to the rebinding step.
miR-26 hence directly binds to the respective 3′ UTR of CHD1, GREB1 or KPNA2 to regulate their expression.
More suggestions(16)
bind to the corresponding
bind to the two
bound to the respective
bind to the mature
bind to the α5β1-domain
bind to the incompatible
bind to the extracellular
bind to the activated
bind to the globular
bind to the immobilized
bind to the hydrophobic
bind to the same
bind to the extensive
relates to the respective
linked to the respective
joined to the respective
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com