Sentence examples for bind to the rat from inspiring English sources
Kitamura et al. (2005) reported that nine separate hydroxylated PCB congeners can bind to the rat TR with an IC50 (half-maximal concentration) as low as 5 μM.
In contrast, 4-acetylaminofluorene, an isomer of 2-AAF, and trans-4-acetylaminostilbene do not bind to the rat hepatic cytosolic Ah receptor.
The murinised version of ATF-BPTI differs by four amino acids from the human version It was shown to bind to the rat receptor and to inhibit plasmin activity in a rat model [ 21].
E5415A made here using the baculovirus display method is an mAb against the extracellular domain of the M23 isoform of mouse AQP4, and could strongly bind to the rat extracellular AQP4 domains, with more than 256 − fold higher affinity as compared with the same dose of D15107 (supplement 3).
It also binds to the rat dopamine D4 receptor, (Kd=4.4 nM), implying similar binding affinity across human and rat receptors.
All of the peptides bound to the rat tachykinin NK1 receptor with high affinity, produced robust calcium signal activation, and led to agonist-induced receptor desensitization.
In the homology model of LvIA bound to the rat α3β2 nAChR, we noticed that Pro-6 of α-CTx LvIA exhibits very strong hydrophobic interactions with Trp-149 of α3 and Trp-57 of the β2 subunit, on the principal and complementary binding sides, respectively.
The assumption was that the label was bound to the rat GnRH-R at these sites.
Within the same cellular context, NR2F2 binds to the rat CYP7A1 promoter causing enhanced transcription [41].
However, Han et al. demonstrated that radiolabeled resveratrol bound to the rat brain plasma membrane fraction with an apparent affinity of 220±45 nM (∼50 ng/ml) and various polyphenols competed against specific resveratrol binding, suggesting that a common receptor binding site was enriched in the brain plasma membrane [21].
Finally, Klf10 was bound to the rat Trh promoter in response to TGFβ in vitro (Martínez-Armenta M. et al. unpublished).
